ABMC Kit – NTL Biologica

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The ABMC Kit provides you with the means to reliably produce bone marrow concentrate and PRP with a clinically validated MSC and growth factor population, within a quick and easy one step procedure.

SYSTEM FEATURES

Cell analysis of BMC samples taken via our system consistently show clinically significant levels of MSCs, with around 3000 healthy MSCs gained per ml of BMC

Our patented centrifuge takes advantage of a larger spin diameter and greater centrifugal force to provide optimum separation and concentration of the sample in
only 6 minutes

The ABMC Kit can be used in conjunction with a variety of clinical and surgical techniques to provide MSC proliferation and differentiation in situ wherever it is required. For example integrated within a Hyaluronic-based scaffold or fibrin glue it has been shown to produce clinically significant results in both chondral and osteochondral lesions only 6 minutes.

USING THE KIT

CLINICAL APPLICATIONS

ORTHOPAEDICS

WOUND HEALING

INFERTILITY

VETERINARY

SURGICAL ADVANTAGES

CELLULAR MICROARCHITECTURE

No oxidation or mechanical impact on the cell population making sure. The tissue preserves its cellular microarchitecture.

STERILITY ASSURANCE

Maximum sterility assurance with maximum security in the working environment.

MINIMAL INJURY

Given the product's ideal size, it can be injected with small needles causing minimal injury during graft implantation.

COMPLETE SINGLE USE KIT

The ABMC kit contains all required harvesting tools suitable for an outpatient surgery setting or a clinic.

SCIENTIFIC EVIDENCE

CHARACTERISATION OF BONE MARROW MESENCHYMAL STEM CELLS

The bone marrow mesenchymal stem cells (BMSCs) isolate d with the ABMC kit were cultured in a flask and characterized according to the International Society for Stem Cell Research. The cells were passaged and characterized using flow cytometry for the positive CD marker expression of CD105, CD29, CD90, and negative CD marker expression of CD34 and CD45. Briefly, 100 000 BMCs were fixed in 4% formalin..’

RETENTION OF STEM CELL CHARACTERISTICS

‘Immunofluorescence staining showed that after 14 days in the gel, the human BMSCs retained their stem cell characteristics as they continued to strongly express CD29 and CD90 (figure below). The spindle-like shape of the cells was clearly visible. and the nucleated cells which were embedded in the gel were able to proliferate into stem cells

Magnification of Bone Marrow MSCs (derived via the
ABMC Kit) cultured in autologous blood glue

EVIDENCE OF CELL VIABILITY

Over 70% of the cells expressed CD29, CD90, and CD105. Additionally, less than 5% of the cell population from this BM aspirate expressed CD34- and CD45.

RETENTION OF KEY STEM CELL CHARACTERISTICS

‘Immunofluorescence staining showed that after 14 days in the gel, the human BMSCs retained their stem cell characteristics as they continued to strongly express CD29 and CD90 (Figure 5). The spindle-like shape of the cells was clearly visible. and the nucleated cells which were embedded in the gel were able to proliferate into stem cells’

The ABMC Kit provides you the freedom to access the therapeutic properties of
both BMC and PRP for your patients
in a variety of clinical settings and at a highly competitive price